Triptorelin
Triptorelin, fatigue
According to copilot:
Triptorelin is a synthetic hormone that acts as a gonadotropin-releasing hormone (GnRH) agonist. It is primarily used to treat:Prostate cancer in men.Central precocious puberty in children, which causes early onset of puberty.Endometriosis in women.Triptorelin works by suppressing the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby reducing testosterone and estrogen levels. Common side effects may include hot flashes, weight gain, and mood changes. For more detailed information, you can refer to sources like Drugs.com and MedlinePlus.
Sources:
A quick skim suggests this is used to suppress puberty in trans youth. It suppresses hormones. It doesn't look to me like it is HRT.
You need either estrogen or testosterone to have a functional immune system. I'm guessing, though I don't know, that they are tired due to lack of hormones.