Cypro, Spiro, rebound
Reddit discussion
Some comments talk about rebound, similar to withdrawal.
Cypro is mentioned. That is probably cyproterone acetate.
Spiro is an anti androgen. Probably short for spironolactone.
I read a good chunk of it. I will note that the body strips bones of calcium to maintain pH balance in the blood so I'm skeptical that blood draws are the optimal means to measure anything in the body and statements about spiro interfering with hitting certain blood levels for estrogen may be extremely misleading as to what is going on.
Beyond that, I'm here to LEARN. I'm not trans and this site is a kind of mad scientist's lab notes.
Here is another anti Spiro piece:
No, I didn't Google "what's bad about spiro."